000			02573cam a22003734a 4500
003			OSt
005			20260408112619.0
008			050623s2006 maua b 001 0 eng
020			_a1405135441 _qpbk. : alk. paper
020			_a9781405135443 _q(pbk. : alk. paper)
040			_aKABLIB _cKABLIB _brda
082	0	0	_a660.65 _223 _bPRI
100	1		_aPrimrose, S. B. _915761
245	1	0	_aPrinciples of gene manipulation and genomics / _cS.B. Primrose and R.M. Twyman.
250			_a7th ed.
260			_aMalden, MA ; _aOxford : _bBlackwell Pub., _c2006.
300			_axxii, 644 p. : _bill.(col) ; _c28 cm.
500			_aRev. ed. of: Principles of gene manipulation. 6th ed. 2001 and Principles of genome analysis and genomics / Sandy B. Primrose, Richard M. Twyman. 3rd ed. 2003.
504			_aIncludes bibliographical references and index.
505	0		_aGene manipulation in the post-genomics era -- Basic techniques -- Cutting and joining DNA molecules -- Basic biology of plasmid and phage vectors -- Cosmids, phasmids, and other advanced vectors -- Gene cloning strategies -- Sequencing genes and short stretches of DNA -- Changing genes : site-directed mutagenesis and protein engineering -- Bioinformatics -- Cloning in bacteria other than Escherichia coli -- Cloning in Saccharomyces cerevisiaea and other fungi -- Gene transfer to animal cells -- Genetic manipulation of animals -- Gene transfer to plants -- Advanced transgenic technology -- The organization and structure of genomes -- Mapping and sequencing genomes -- Comparative genomics -- Large-scale mutagenesis and interference -- Analysis of the transcriptome -- Proteomics I : expression analysis and characterization of proteins -- Proteomics II : analysis of protein structures -- Proteomics III : protein interactions -- Metabolomics and global biochemical networks -- Applications of genomics : understanding the basis of polygenic disorders and identifying quantitative trait loci -- Applications of recombinant DNA technology.
650		0	_aGenetic engineering. _914069
650		0	_aGenomics. _913906
650		0	_aGene mapping. _915762
650		0	_aNucleotide sequence. _915763
650	1	2	_aGenetic Engineering. _914069
650	2	2	_aBase Sequence. _915764
650	2	2	_aChromosome Mapping. _915765
650	2	2	_aDNA, Recombinant. _915766
650	2	2	_aGenomics. _913906
700	1		_aTwyman, Richard M. _915767
700	1		_aPrimrose, S. B. _tPrinciples of gene manipulation. _915768
700	1		_aPrimrose, S. B. _tPrinciples of genome analysis and genomics. _915769
942			_2ddc _cBOOK
999			_c6199 _d6199